Colgate* Total* toothpaste With Triclosan:
THE TRUSTED CHOICE OF DENTISTS


Colgate* Total* has been the trusted choice for healthy teeth and gums for more than 20 years. Worldwide, it’s the brand recommended most by dentists for everyday use

Colgate* Total* toothpaste is specially formulated with 0.3% of the antibacterial ingredient triclosan to fight harmful plaque germs, which are the cause of most common oral health problems.

There are more published, peer-reviewed clinical studies of Colgate* Total* than of any other toothpaste in the world. The efficacy and safety of Colgate* Total* is supported by more than 90 clinical studies, involving over 20,000 people, and a broad set of safety evaluations. Reviews by Health Canada, and other government agencies and independent sources around the world, confirm that triclosan in toothpaste is safe for human health, and recognize that triclosan in toothpaste, such as that found in Colgate* Total* toothpaste, provides an oral health benefit.

Colgate* Total* has gone through the rigorous Canadian New Drug Submission (NDS) review process, the same process used to license prescription medications for sale in Canada. The NDS process requires a comprehensive evaluation of human safety. All new drug assessments include a review of nonclinical studies covering a wide array of toxicological endpoints such as carcinogenicity, reproductive and developmental toxicity, eye and skin irritation, and short term and long term toxicity.

Colgate* Total* toothpaste is clinically proven to provide 12-hour protection against plaque germs that can lead to gingivitis, an early form of gum disease. Plaque and gingivitis, if unchecked, can progress to periodontitis, a more serious and damaging stage of infection that can result in tooth and bone loss.

Brushing with regular fluoride toothpaste does not provide the antibacterial protection of Colgate* Total* toothpaste. On the US FDA’s website, updated as of September 2, 2016, the FDA states as follows regarding Colgate* Total* toothpaste: "For some consumer products, there is evidence that triclosan provides a benefit." The FDA notes that it has “reviewed extensive effectiveness data on triclosan in Colgate* Total* toothpaste" and that the "evidence showed that triclosan in that product was effective in preventing gingivitis. Similarly, the Government of Canada has previously recognized the benefit, and indicates on their website: “Triclosan provides some health benefits in non-prescription drug products, such as its use in toothpaste to protect against gingivitis.”

A thorough independent review was conducted and published by the Cochrane Oral Health Group on the oral health benefits of triclosan/copolymer, the active antibacterial system in Colgate* Total* toothpaste. The Cochrane Review evaluated 30 studies dating from 1990 to 2012 and involving 14,835 participants (Riley & Lamont 2013). The resulting data highlighted the many clinical benefits of using a fluoride toothpaste containing triclosan/copolymer and concluded there was no evidence of any harmful effects associated with the use of triclosan/copolymer toothpastes in studies up to three years in duration.

View the full text of the Cochrane Review

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